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22nd Mar, 2024 12:00 AM
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Hysterectomy Avoided With Uterine Embolization After Birth

TOPLINE:

A new study presented at the Society of Interventional Radiology Annual Scientific Meeting concludes that uterine artery embolization (UAE) had a high rate of success in controlling postpartum bleeding, obviating the need for hysterectomies in many patients.

METHODOLOGY:

  • UAE is a minimally invasive procedure that entails an interventional radiologist injects tiny particles that will temporarily block the blood flow into uterine arteries.
  • The authors conducted a retrospective review of 66 patients (median age, 31 years) who underwent UAE for postpartum hemorrhage between 2014 and 2022.
  • The median time between the start of a postpartum hemorrhage and UAE was 4 hours but also ranged up to 15 days after.
  • Patients lost a median of 2790 mL of blood, and a pre-embolization transfusion was administered in over 80% of women.

TAKEAWAY:

  • Successful hemorrhage control was achieved in 94% of the patients; those who experienced greater blood loss prior to UAE were more likely to develop post-embolization syndrome, which is marked by fever, abdominal pain, and nausea.
  • The overall infertility rate after UAE was 19%.
  • Higher fibrinogen levels prior to embolization were associated with better hemorrhage control.

IN PRACTICE:

"Based on these findings, we would encourage obstetricians to involve interventional radiologists early, to be ready to perform UAE if more conservative approaches are not managing postpartum hemorrhage."

SOURCE:

The study was led by Younes Jahangiri, MD, a resident in the interventional and diagnostic radiology program at Michigan State University/Corewell Health. James Morrison, MD, assistant professor of interventional radiology, also at Michigan State University/Corewell Health, was the senior author.

LIMITATIONS:

This was a retrospective review with a relatively small sample size.

DISCLOSURES:

No disclosures were reported.

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