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11th Feb, 2026 12:00 AM
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More Than a Third Of Patients on Wegovy Pill Are New to GLP-1 Drugs, Study Finds

SAN FRANCISCO, Feb 11 (Reuters) - Among early users of Novo Nordisk's new Wegovy weight-loss pill, 36% had no prior experience taking ⁠a GLP-1 medication, a new nationwide study from the health data firm Truveta found.

Of patients who started a new pill prescription, ⁠21.1% had previously taken the injectable version of Wegovy and 15.8% switched from Eli Lilly's Zepbound, another ⁠injectable GLP-1 medicine, according to Truveta data.

The ‌Wegovy pill is the first oral GLP-1 drug approved to treat chronic weight management, creating a new option for patients and providers who might not want an injectable medicine.

The fast uptake among those without prior experience with GLP-1 drugs shows that the oral medication is reaching new patients rather ‌than just taking market share from the injectables, something analysts and investors have ​been eager ‌to gauge.

Truveta reviewed health records from 8,762 ‌U.S. patients with evidence of a prescription written or filled for the new Wegovy pill, which won U.S. approval ⁠on December 22.

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During the first six weeks that the pill ‌has been available to ⁠patients, Truveta found that 73.3% of ​those with prescriptions are female, 72.8% are ‌white and 71.6% live in urban areas. The group also skewed older as 34% were ages 45 to 59 years, and 37.8% were age 60 or older.

The data offers an early ​glimpse of patients on oral Wegovy, which may change over ‌time.

For ‌example, more patients currently taking injectable GLP-1 medicines may switch to the pill in the coming weeks, ‌after they finish their ​current supply, Truveta noted.

A rival oral weight-loss medication from Lilly is expected to be approved in April.

Novo is selling lower doses of its daily pill in the United ⁠States for $149 per month for self-paying patients, rising to $199 in April.

In January, ‌Truveta reported that prescriptions for GLP-1 therapies now account for over 7% of all prescriptions ​nationwide.

(Reporting by Robin RespautEditing by Bill Berkrot)


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