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9th Mar, 2026 12:00 AM
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Pfizer's Eczema Drug Meets Main Goal in Mid-stage Trial, Plans Late-stage Study

* The ⁠patients treated with the drug, tilrekimig, saw asignificant reduction in symptoms after ⁠16 weeks and the ‌drugwas well tolerated with a favorable safety profile in the study,Pfizer said. * The drug is currently being tested in patients withmoderate to severe atopic dermatitis or eczema, a skin diseasethat causes itching, widespread ‌rashes and inflammation that candisrupt daily activities. * BMO analyst ​Evan Seigerman ‌said the trial results point ‌toa potentially competitive profile in atopic dermatitis, withhigher initial efficacy than Regeneron and Sanofi's ⁠blockbusterDupixent. * Seigerman said the readout gives ‌Pfizer another potentialcatalyst ⁠as it works to ​rebuild momentum across its pipeline,but ‌cautioned that more detailed safety and placebo‑responsedata will be critical. * Across three doses, the share of patients with strongimprovement was 38.7%, 51.9% ​and 49.4%, which were higher thanplacebo. * Based ‌on ‌the results, Pfizer said it plans to move thedrug into late-stage ‌testing for eczema, ​with the trial expectedto begin this year. * Pfizer plans to develop the drug for asthma and chronicobstructive pulmonary disease. * ⁠The current treatment landscape for eczema includesestablished drugs such ‌as AbbVie's Rinvoq and Eli Lilly'sEbglyss.

March 9 (Reuters) - U.S. drugmaker Pfizer said on Monday its experimental drug for a ⁠chronic skin disease met the main goal in a mid-stage study.

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(Reporting by Padmanabhan Ananthan in ​Bengaluru; Editing by Mrigank Dhaniwala)


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