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13th May, 2026 12:00 AM
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US Drug Overdose Deaths Dropped for Third Straight Year in 2025, CDC Data Shows

May 13 (Reuters) - Drug overdose deaths in the United States fell nearly ⁠14% in 2025, federal estimates showed on Wednesday, marking a third ⁠consecutive year of declines.

Here are some details:

• Nearly 69,973 ⁠people died from ‌drug overdose in the U.S. in 2025, compared with 81,313 deaths estimated a year earlier, according to provisional data from the U.S. Centers for ‌Disease Control and Prevention.

• The wide availability ​of a ‌medication called naloxone, ‌a potent overdose antidote, has significantly contributed to the drop, ⁠according to experts.

• Deaths involving ‌opioids fell to ⁠an estimated ​44,564 in 2025 from ‌55,296 a year earlier, the CDC estimates showed.

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• Synthetic opioids, including Fentanyl, are the single largest ​contributor to overdose deaths in ‌the ‌country.

• While most states across the nation showed ‌declines in ​overdose deaths, New Mexico, Arizona and Colorado had increases of 10% or more compared ⁠to the same period in 2024, the ‌report said.

(Reporting by Mariam Sunny in Bengaluru; ​Editing by Shailesh Kuber)


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